Research
Women's Health Initiative
PI |
Jean Wactawski-Wende, PhD and Maurizio Trevisan, MD, MS |
|---|---|
Funding Agency |
NHLBI |
Period |
3/15/93 - 9/14/05, WHI Extension study 9/16/05 - 9/30/10 |
The Women's Health Initiative is a large multi-center Clinical Trial
(WHI) and Observational Study (OS) studying the major causes of
morbidity and mortality in postmenopausal women. This primary prevention
trial and observational study has assessed the role of hormone therapy,
diet and calcium / vitamin D supplementation on heart disease, cancer
and osteoporosis in postmenopausal women. The WHI is a national
study supported by the National Institutes of Health (NHLBI). Buffalo
is one of 40 WHI centers nationally.
The Buffalo center is directed by Principal Investigators Dr. Jean Wactawski-Wende and Dr. Maurizio Trevisan. There are three (3) clinical trials: Hormone Therapy vs. Placebo (2 trials), Diet Modification vs. Usual Diet and Calcium/Vitamin D Supplementation vs. Placebo. The Buffalo WHI Clinical Center was one of the original vanguard centers for the WHI.
Nationwide, there are over 160,000 participants enrolled in the WHI. Locally, there are nearly 4,000 participants from western New York.
The primary endpoints of the three WHI clinical trials have been published. Further results from these studies will continue to be published.
In 2005, the University at Buffalo was awarded the WHI Extension Study. This is a 5-year follow-up study that will assess the longer term outcomes of these studies.
Contact Information:
Dr. Jean Wactawski-Wende
Department of Social and Preventive Medicine
65 Farber Hall
3435 Main Street (South Campus)
Buffalo, NY 14214-8001
716-829-3128
Further Information:
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